{"id":42609,"date":"2025-03-20T17:55:00","date_gmt":"2025-03-20T14:55:00","guid":{"rendered":"https:\/\/www.enbiosis.com\/?page_id=42609"},"modified":"2025-05-06T17:01:29","modified_gmt":"2025-05-06T14:01:29","slug":"alzehimers-disease","status":"publish","type":"post","link":"https:\/\/enbiosis.com\/staging\/alzehimers-disease\/","title":{"rendered":"The Gut-Brain Connection: Unlocking Alzheimer\u2019s Prevention!"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_33 counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" style=\"display: none;\"><label for=\"item\" aria-label=\"Table of Content\"><i class=\"ez-toc-glyphicon ez-toc-icon-toggle\"><\/i><\/label><input type=\"checkbox\" id=\"item\"><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1'><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/enbiosis.com\/staging\/alzehimers-disease\/#How_Does_the_Gut_Microbiome_Influence_Alzheimers_Disease\" title=\"How Does the Gut Microbiome Influence Alzheimer\u2019s Disease?\">How Does the Gut Microbiome Influence Alzheimer\u2019s Disease?<\/a><ul class='ez-toc-list-level-2'><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/enbiosis.com\/staging\/alzehimers-disease\/#How_Does_the_Gut_Microbiome_Affect_Cognitive_Health\" title=\"How Does the Gut Microbiome Affect Cognitive Health?\">How Does the Gut Microbiome Affect Cognitive Health?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/enbiosis.com\/staging\/alzehimers-disease\/#Alzheimers_and_Gut_Dysbiosis_What_Does_the_Science_Say\" title=\"Alzheimer\u2019s and Gut Dysbiosis: What Does the Science Say?\">Alzheimer\u2019s and Gut Dysbiosis: What Does the Science Say?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/enbiosis.com\/staging\/alzehimers-disease\/#Can_Restoring_the_Gut_Microbiome_Help_to_Protect_the_Brain\" title=\"Can Restoring the Gut Microbiome Help to Protect the Brain?\">Can Restoring the Gut Microbiome Help to Protect the Brain?<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/enbiosis.com\/staging\/alzehimers-disease\/#Enbiosis_Science-Backed_Approach_to_Brain_Health\" title=\"Enbiosis\u2019 Science-Backed Approach to Brain Health\">Enbiosis\u2019 Science-Backed Approach to Brain Health<\/a><\/li><\/ul><\/nav><\/div>\n<h1 style=\"text-align: center;\"><span class=\"ez-toc-section\" id=\"How_Does_the_Gut_Microbiome_Influence_Alzheimers_Disease\"><\/span><strong>How Does the Gut Microbiome Influence Alzheimer\u2019s Disease?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<div style=\"width: 1020px;\" class=\"wp-video\"><!--[if lt IE 9]><script>document.createElement('video');<\/script><![endif]-->\n<video class=\"wp-video-shortcode\" id=\"video-42609-1\" width=\"1020\" height=\"574\" preload=\"metadata\" controls=\"controls\"><source type=\"video\/mp4\" src=\"https:\/\/www.enbiosis.com\/wp-content\/uploads\/2025\/03\/Untitled-4.mp4?_=1\" \/><a href=\"https:\/\/www.enbiosis.com\/wp-content\/uploads\/2025\/03\/Untitled-4.mp4\">https:\/\/www.enbiosis.com\/wp-content\/uploads\/2025\/03\/Untitled-4.mp4<\/a><\/video><\/div>\n<a href=\"http:\/\/\" target=\"https:\/\/www.enbiosis.com\/contact-us\/\" class=\"button primary is-primary is-medium\"  >\n    <span>Learn More<\/span>\n  <\/a>\n\n<p>Alzheimer\u2019s disease is a form of dementia, a condition that affects more than 55 million individuals worldwide, with cases expected to rise to 139 million by 2050 (1) As the leading cause of dementia, Alzheimer\u2019s disease accounts for between 60 and 70% of these cases (2) Like other types of dementia, this devastating neurodegenerative disorder is characterized by memory loss, cognitive decline, language problems and behavioral changes.<\/p>\n<p>Despite decades of research into Alzheimer\u2019s and dementia, there is currently no cure, and medical treatments can only offer limited relief. But what if the key to slowing, or even preventing Alzheimer\u2019s isn\u2019t just in the brain, but in the gut? Traditionally, research has focused on the effects of genetic factors on our brain pathology, but researchers are now shifting their attention elsewhere\u2014to the microbes living within our digestive system.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_Does_the_Gut_Microbiome_Affect_Cognitive_Health\"><\/span><strong>How Does the Gut Microbiome Affect Cognitive Health?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Our gut microbiome has a profound effect on many aspects of our health, including our brain function. The microbes in our gut communicate with our brain via a complex system known as the gut-brain axis. This means that changes in the composition of our gut microbiome can influence our mood, behavior, and cognitive functions. <\/span><span style=\"font-weight: 400;\">One of the key ways the gut microbiome influences our cognitive health is by modulating our immune system. The gut is home to between 70 and 80% of our body\u2019s immune cells (3)<\/span><span style=\"font-weight: 400;\">, and imbalances in our gut bacteria can lead to chronic inflammation. This inflammation can trigger neuroinflammation in the brain, a factor believed to contribute to cognitive decline associated with neurodegenerative diseases such as Alzheimer\u2019s. (4)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The gut microbiome also regulates the production, movement and function of key neurotransmitters within our brain, including serotonin, dopamine and gamma-aminobutyric acid (GABA) (5)<\/span><span style=\"font-weight: 400;\">\u00a0Gut dysbiosis, or an imbalance of gut bacteria, can disrupt the production of these important neurotransmitters.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Additionally, the gut microbiome and its metabolites have an impact on the integrity of the blood-brain barrier (BBB), which serves as a selective shield, protecting the brain from harmful substances. When the microbiome is out of balance, it can increase the permeability of the BBB, allowing harmful compounds to enter the brain (6)<\/span><span style=\"font-weight: 400;\">\u00a0These compounds can promote inflammation and damage to the brain tissue. <\/span><span style=\"font-weight: 400;\">Recent evidence also suggests that our gut microbes could be involved in the production and regulation of amyloid-beta (A\u03b2), a key protein linked to Alzheimer&#8217;s disease (7).<\/span><span style=\"font-weight: 400;\"> The accumulation of A\u03b2 proteins in the brain forms amyloid plaques, which are one of the hallmark features of Alzheimer\u2019s.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lastly, the gut microbiome produces short-chain fatty acids (SCFAs) such as acetic acid, propionic acid, and butyric acid, during the fermentation of dietary fiber. SCFAs have anti-inflammatory properties and help to protect the brain from neurodegenerative diseases by regulating inflammatory pathways, as well as the formation of amyloid plaques and tau protein hyperphosphorylation. (8)<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Alzheimers_and_Gut_Dysbiosis_What_Does_the_Science_Say\"><\/span><strong><img fetchpriority=\"high\" decoding=\"async\" class=\"alignright wp-image-42611 size-full\" src=\"https:\/\/www.enbiosis.com\/wp-content\/uploads\/2025\/03\/Untitled-design-6-e1721292577834.jpg\" alt=\"\" width=\"769\" height=\"500\" srcset=\"https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/Untitled-design-6-e1721292577834.jpg 769w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/Untitled-design-6-e1721292577834-300x195.jpg 300w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/Untitled-design-6-e1721292577834-510x332.jpg 510w\" sizes=\"(max-width: 769px) 100vw, 769px\" \/>Alzheimer\u2019s and Gut Dysbiosis: What Does the Science Say?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Multiple studies have demonstrated distinct differences in the gut microbiomes of Alzheimer\u2019s patients compared to those of healthy controls. These differences often involve a reduction in gut microbial diversity, as well as significant alterations in the relative abundance of specific bacterial species.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For instance, one study demonstrated that Alzheimer\u2019s disease (AD) patients have a gut microbiome population that is distinct from that of sex- and age-matched controls. A marked reduction in overall microbiome diversity was observed, with decreased levels of <\/span><i><span style=\"font-weight: 400;\">Firmicutes <\/span><\/i><span style=\"font-weight: 400;\">and <\/span><i><span style=\"font-weight: 400;\">Bifidobacterium <\/span><\/i><span style=\"font-weight: 400;\">and a corresponding increase in <\/span><i><span style=\"font-weight: 400;\">Bacteroidetes (9)<\/span><\/i><span style=\"font-weight: 400;\">.<\/span><span style=\"font-weight: 400;\"> Another study similarly found lower <\/span><i><span style=\"font-weight: 400;\">Firmicutes <\/span><\/i><span style=\"font-weight: 400;\">levels and increased <\/span><i><span style=\"font-weight: 400;\">Proteobacteria <\/span><\/i><span style=\"font-weight: 400;\">in AD patients (10)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">More specifically, one study identified a significant decrease in butyrate-producing bacteria, such as <\/span><i><span style=\"font-weight: 400;\">Faecalibacterium <\/span><\/i><span style=\"font-weight: 400;\">in AD patients, alongside a marked increase in lactate-producing bacteria, including <\/span><i><span style=\"font-weight: 400;\">Bifidobacterium (11)<\/span><\/i><span style=\"font-weight: 400;\"> Since butyrate plays a key role in reducing inflammation and maintaining gut barrier integrity, its depletion may contribute to the systemic inflammation seen in Alzheimer\u2019s disease.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Further evidence of this inflammatory link comes from research showing a significant increase in pro-inflammatory bacteria, including <\/span><i><span style=\"font-weight: 400;\">Escherichia <\/span><\/i><span style=\"font-weight: 400;\">and <\/span><i><span style=\"font-weight: 400;\">Shigella <\/span><\/i><span style=\"font-weight: 400;\">and a reduction in the anti-inflammatory species <\/span><i><span style=\"font-weight: 400;\">Eubacterium rectale<\/span><\/i><span style=\"font-weight: 400;\"> in individuals with cognitive impairment and brain amyloidosis (12) <\/span><span style=\"font-weight: 400;\">This suggests that gut dysbiosis may trigger a chronic inflammatory state that exacerbates neurodegeneration.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Importantly, gut dysbiosis does not only emerge in late-stage Alzheimer\u2019s\u2014it actually appears early in the disease process and worsens over time. Studies indicate that patients newly diagnosed with AD already exhibit gut microbiome imbalances, including a decrease in potentially protective bacteria such as <\/span><i><span style=\"font-weight: 400;\">Bacteroides <\/span><\/i><span style=\"font-weight: 400;\">and an increase in pro-inflammatory species such as <\/span><i><span style=\"font-weight: 400;\">Prevotella (13)<\/span><\/i><\/p>\n<p><span style=\"font-weight: 400;\">Notably, another study demonstrated that the gut microbiome composition changes progressively with increasing severity of Alzheimer&#8217;s disease. As cognitive impairment worsened, the abundance of <\/span><i><span style=\"font-weight: 400;\">Firmicutes <\/span><\/i><span style=\"font-weight: 400;\">and <\/span><i><span style=\"font-weight: 400;\">Bacteroides <\/span><\/i><span style=\"font-weight: 400;\">within the gut gradually decreased, while <\/span><i><span style=\"font-weight: 400;\">Proteobacteria<\/span><\/i><span style=\"font-weight: 400;\">, <\/span><i><span style=\"font-weight: 400;\">Verrucomicrobia<\/span><\/i><span style=\"font-weight: 400;\">, and <\/span><i><span style=\"font-weight: 400;\">Actinobacteria <\/span><\/i><span style=\"font-weight: 400;\">levels increased (14)<\/span><span style=\"font-weight: 400;\">\u00a0These shifts highlight a clear microbial signature associated with disease progression, reinforcing the potential role of gut dysbiosis in driving neurodegeneration.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Collectively, these findings indicate that gut microbiome imbalances are not just present in Alzheimer&#8217;s disease\u2014they emerge early and evolve as the disease worsens. This raises an important question: could modifying the gut microbiome help to slow or even prevent cognitive decline?<\/span><\/p>\n<h2><span class=\"ez-toc-section\" id=\"Can_Restoring_the_Gut_Microbiome_Help_to_Protect_the_Brain\"><\/span><strong><img decoding=\"async\" class=\"alignleft wp-image-42610\" src=\"https:\/\/www.enbiosis.com\/wp-content\/uploads\/2025\/03\/DALL\u00b7E-2025-03-20-17.32.48-A-conceptual-illustration-of-the-connection-between-the-gut-microbiome-and-Alzheimers-disease-featuring-the-Enbiosis-logo.-The-image-showcases-a-hum-300x300.webp\" alt=\"\" width=\"400\" height=\"400\" srcset=\"https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/DALL\u00b7E-2025-03-20-17.32.48-A-conceptual-illustration-of-the-connection-between-the-gut-microbiome-and-Alzheimers-disease-featuring-the-Enbiosis-logo.-The-image-showcases-a-hum-300x300.webp 300w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/DALL\u00b7E-2025-03-20-17.32.48-A-conceptual-illustration-of-the-connection-between-the-gut-microbiome-and-Alzheimers-disease-featuring-the-Enbiosis-logo.-The-image-showcases-a-hum-150x150.webp 150w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/DALL\u00b7E-2025-03-20-17.32.48-A-conceptual-illustration-of-the-connection-between-the-gut-microbiome-and-Alzheimers-disease-featuring-the-Enbiosis-logo.-The-image-showcases-a-hum-768x768.webp 768w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/DALL\u00b7E-2025-03-20-17.32.48-A-conceptual-illustration-of-the-connection-between-the-gut-microbiome-and-Alzheimers-disease-featuring-the-Enbiosis-logo.-The-image-showcases-a-hum-510x510.webp 510w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/DALL\u00b7E-2025-03-20-17.32.48-A-conceptual-illustration-of-the-connection-between-the-gut-microbiome-and-Alzheimers-disease-featuring-the-Enbiosis-logo.-The-image-showcases-a-hum-100x100.webp 100w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/DALL\u00b7E-2025-03-20-17.32.48-A-conceptual-illustration-of-the-connection-between-the-gut-microbiome-and-Alzheimers-disease-featuring-the-Enbiosis-logo.-The-image-showcases-a-hum.webp 1024w\" sizes=\"(max-width: 400px) 100vw, 400px\" \/>Can Restoring the Gut Microbiome Help to Protect the Brain?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Dietary modifications can significantly influence our gut microbiome and, by extension, our brain health. In recent years, a growing body of research has supported the idea that modulating our gut microbiome through informed dietary and lifestyle changes offers promising potential for protecting our brain from neurodegenerative diseases such as Alzheimer&#8217;s and dementia.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In support of this, a 2023 review article highlights the promising potential of gut microbiome-targeted therapies in improving outcomes for Alzheimer&#8217;s patients. The reviewed findings indicate a significant relationship between gut health and the progression of AD, suggesting that restoring a healthy gut microbiota may alleviate symptoms and slow disease development. Various interventions, including probiotics, prebiotics and synbiotics are explored as potential therapeutic strategies, with encouraging data from early preclinical and some clinical studies. (15)<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, to maximize the efficiency of microbiome-targeting therapies, a personalized approach is crucial. Each individual\u2019s microbiome is unique, and this means that tailoring interventions to a person\u2019s specific gut profile will yield the best results. For instance, different probiotic strains may have varying effects on cognitive function. This was shown in a 2022 study where 90 patients with mild to moderate AD were given either <\/span><i><span style=\"font-weight: 400;\">Lactobacillus rhamnosus<\/span><\/i><span style=\"font-weight: 400;\"> or <\/span><i><span style=\"font-weight: 400;\">Bifidobacterium longum <\/span><\/i><span style=\"font-weight: 400;\">supplements, or a placebo, twice daily for 12 weeks (16)<\/span><span style=\"font-weight: 400;\">\u00a0Participants taking the <\/span><i><span style=\"font-weight: 400;\">B. longum<\/span><\/i><span style=\"font-weight: 400;\"> probiotic supplement experienced a greater improvement in cognition compared to both the placebo and <\/span><i><span style=\"font-weight: 400;\">L. rhamnosus<\/span><\/i><span style=\"font-weight: 400;\"> groups. This highlights the importance of testing your microbiome, as it can reveal bacteria that are either lacking or in excess, allowing for targeted interventions that are more likely to be effective.<\/span><\/p>\n<h1><span class=\"ez-toc-section\" id=\"Enbiosis_Science-Backed_Approach_to_Brain_Health\"><\/span><strong><img decoding=\"async\" class=\"alignleft wp-image-42105 size-full\" src=\"https:\/\/www.enbiosis.com\/wp-content\/uploads\/2025\/03\/product-all.png\" alt=\"\" width=\"1666\" height=\"738\" srcset=\"https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/product-all.png 1666w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/product-all-300x133.png 300w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/product-all-768x340.png 768w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/product-all-1536x680.png 1536w, https:\/\/enbiosis.com\/staging\/wp-content\/uploads\/2025\/03\/product-all-510x226.png 510w\" sizes=\"(max-width: 1666px) 100vw, 1666px\" \/>Enbiosis\u2019 Science-Backed Approach to Brain Health<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><span style=\"font-weight: 400;\">At Enbiosis, we offer a cutting-edge, AI-powered gut microbiome testing service that helps uncover any imbalances that could be affecting your brain health. We provide insights into your gut health, as well as personalized food recommendations, and suggestions for prebiotics and probiotics, all backed by the latest scientific research. <\/span><a href=\"https:\/\/www.enbiosis.com\/contact-us\/\"><span style=\"font-weight: 400;\">Contact us<\/span><\/a><span style=\"font-weight: 400;\"> today to discover more about our approach and find out how we can support you with our evidence-based solutions.\u00a0\u00a0<\/span><\/p>\n<a class=\"button primary is-primary is-medium\"  >\n    <span>Learn More<\/span>\n  <\/a>\n\n<p><strong>References<\/strong><\/p>\n<p>1 World Health Organization. (\u200e2021)\u200e. Global status report on the public health response to dementia. World Health Organization. https:\/\/digitalcommons.fiu.edu\/srhreports\/health\/health\/65\/<br \/>\n2 World Health Organization. (2023). Dementia. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dementia<br \/>\n3 Wiertsema, S. P., Garssen, J., &amp; J Knippels, L. M. (2021). The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies. <em>Nutrients, 13<\/em>(3), 886.<br \/>\n4 Heneka, M. T., M., W., Jessen, F., Hoozemanns, J., Thal, D. R., Boche, D., Brosseron, F., Teunissen, C., Zetterberg, H., Jacobs, A. H., Edison, P., Ramirez, A., Cruchaga, C., Lambert, J., Laza, A. R., Vicente, J., Fischer, A., Stein, T. D., Kleineidam, L., Riechers, S et al. (2024). Neuroinflammation in Alzheimer disease.<em> Nature Reviews Immunology, <\/em>1-32.<br \/>\n5 Chen, Y., Xu, J., &amp; Chen, Y. (2021). Regulation of Neurotransmitters by the Gut Microbiota and Effects on Cognition in Neurological Disorders. <em>Nutrients, 13.<br \/>\n<\/em>6 Xie, J., Bruggeman, A., De Nolf, C., Vandendriessche, C., Van Imschoot, G., Van Wonterghem, E., Vereecke, L., &amp; Vandenbroucke, R. E. (2023). Gut microbiota regulates blood\u2010cerebrospinal fluid barrier function and A\u03b2 pathology. <em>EMBO Journal, 42<\/em>(17), e111515.<br \/>\n6 Jin, J., Xu, Z., Zhang, L., Zhang, C., Zhao, X., Mao, Y., Zhang, H., Liang, X., Wu, J., Yang, Y., &amp; Zhang, J. (2023). Gut-derived \u03b2-amyloid: Likely a centerpiece of the gut\u2013brain axis contributing to Alzheimer\u2019s pathogenesis.<em> Gut Microbes, 15<\/em>(1), 2167172<br \/>\n7 Qian, X. H., Xie, R. Y., Liu, X. L., Chen, S. D., &amp; Tang, H. D. (2022). Mechanisms of Short-Chain Fatty Acids Derived from Gut Microbiota in Alzheimer&#8217;s Disease. <em>Aging and Disease, 13<\/em>(4), 1252\u20131266.<br \/>\n8 Vogt, N. M., Kerby, R. L., Dill-McFarland, K. A., Harding, S. J., Merluzzi, A. P., Johnson, S. C., Carlsson, C. M., Asthana, S., Zetterberg, H., Blennow, K., Bendlin, B. B., &amp; Rey, F. E. (2017). Gut microbiome alterations in Alzheimer\u2019s disease.<em> Scientific Reports, 7, <\/em>13537.<br \/>\n9 Liu, P., Wu, L., Peng, G., Han, Y., Tang, R., Ge, J., Zhang, L., Jia, L., Yue, S., Zhou, K., Li, L., Luo, B., &amp; Wang, B. (2019). Altered microbiomes distinguish Alzheimer\u2019s disease from amnestic mild cognitive impairment and health in a Chinese cohort. <em>Brain, Behavior, and Immunity, 80, <\/em>633-643.<br \/>\n10 Ling, Z., Zhu, M., Yan, X., Cheng, Y., Shao, L., Liu, X., Jiang, R., &amp; Wu, S. (2021). Structural and Functional Dysbiosis of Fecal Microbiota in Chinese Patients With Alzheimer&#8217;s Disease. <em>Frontiers in Cell and Developmental Biology, 8,<\/em> 634069.<br \/>\n11 Cattaneo, A., Cattane, N., Galluzzi, S., Provasi, S., Lopizzo, N., Festari, C., Ferrari, C., Guerra, U. P., Paghera, B., Muscio, C., Bianchetti, A., Volta, G. D., Turla, M., Cotelli, M. S., Gennuso, M., Prelle, A., Zanetti, O., Lussignoli, G., Mirabile, D., Bellandi, D., et al. (2017). Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly. <em>Neurobiology of Aging, 49, <\/em>60\u201368.<br \/>\n12 Guo, M., Peng, J., Huang, X., Xiao, L., Huang, F., &amp; Zuo, Z. (2021). Gut Microbiome Features of Chinese Patients Newly Diagnosed with Alzheimer&#8217;s Disease or Mild Cognitive Impairment. <em>Journal of Alzheimer&#8217;s disease : JAD, 80<\/em>(1), 299\u2013310.<br \/>\n13 Chen, L., Xu, X., Wu, X., Cao, H., Li, X., Hou, Z., Wang, B., Liu, J., Ji, X., Zhang, P., &amp; Li, H. (2022). A comparison of the composition and functions of the oral and gut microbiotas in Alzheimer\u2019s patients. <em>Frontiers in Cellular and Infection Microbiology, 12<\/em>, 942460.<br \/>\n14 Zhang, T., Gao, G., Kwok, L. Y., &amp; Sun, Z. (2023). Gut microbiome-targeted therapies for Alzheimer&#8217;s disease. <em>Gut microbes, 15<\/em>(2), 2271613.<br \/>\n15 Akhgarjand, C., Vahabi, Z., Etesam, F., &amp; Djafarian, K. (2022). Effects of probiotic supplements on cognition, anxiety, and physical activity in subjects with mild and moderate Alzheimer\u2019s disease: A randomized, double-blind, and placebo-controlled study.<em> Frontiers in Aging Neuroscience, 14,<\/em> 1032494.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>How Does the Gut Microbiome Influence Alzheimer\u2019s Disease? Alzheimer\u2019s disease is a form of dementia, a condition that affects more than 55 million individuals worldwide, with cases expected to rise to 139 million by 2050 (1) As the leading cause of dementia, Alzheimer\u2019s disease accounts for between 60 and 70% of these cases (2) Like [&#8230;]\n","protected":false},"author":477,"featured_media":42610,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"om_disable_all_campaigns":false,"inline_featured_image":false,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[1601],"tags":[],"class_list":["post-42609","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-new-blogs"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Gut-Brain Connection: Unlocking Alzheimer\u2019s Prevention! - Enbiosis<\/title>\n<meta name=\"description\" content=\"Discover the crucial link between the gut microbiome and Alzheimer\u2019s disease. Learn how gut health impacts brain function, cognitive decline, and neuroinflammation. Explore science-backed solutions with AI-powered microbiome analysis from Enbiosis for personalized brain health support.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Gut-Brain Connection: Unlocking Alzheimer\u2019s Prevention! - Enbiosis\" \/>\n<meta property=\"og:description\" content=\"Discover the crucial link between the gut microbiome and Alzheimer\u2019s disease. Learn how gut health impacts brain function, cognitive decline, and neuroinflammation. 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