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Enbiosis “The World’s First Digital Twin & AI Powered Nutraceutical Formulation Engine”

Science & Technology

From Microbiome Science to Market-Ready Formulations

  • 15+Years R&D
  • Publications in Top Q1 Journals
  • 10+Active Patents

Enbiosis began as an AI-powered, microbiome-based personalized food and supplement recommendations platform. Over time, this foundation evolved into a design engine that models and predicts these transformations to guide targeted formulation development.

Our Story

The Scientific Evolution of Enbiosis

Enbiosis began as an AI-powered, microbiome-based personalized food and supplement recommendations platform. Over 15+ years of experience, our unique algorithm has been validated through four Q1 publications and partnerships across the UK, the US, Canada, Latin America, the Middle East and Southeast Asia.

Building on this foundation, we evolved beyond personalized recommendations into a formulation platform. Translating microbiome insights into targeted nutraceutical designs.

The result is Enbiosis 2.0: a formulation engine powered by Digital Twin & AI, supported by clinical evidence.

  • 15+Years of Experience
  • Publications in Top Q1 Journals

  1. Step 1

    Digital Twin Modeling

    Developing digital twin models of the human gut microbiome to simulate how microbial communities process different inputs and generate metabolic outputs.

  2. Step 2

    Metabolic Pathway Identification

    Identifying target metabolic pathways and key microbial functions associated with specific health outcomes through simulation and scientific validation.

  3. Step 3

    Retrosynthetic Formulation Design

    Using AI-driven retrosynthesis to identify food-grade precursors that can be converted by the microbiome into target metabolites.

  4. Step 4

    Formulation & Deployment

    Translating these insights into ready-to-use nutraceutical formulations, designed for scalable integration across global markets.

The Technology

We Simulate The Gut Microbiome

Through digital twin technology, we identify condition-specific metabolic targets and design research-backed, food-grade formulations to support outcomes across gastrointestinal, ocular, cognitive, mental health, and beyond.

Standard Approach

Trial-and-Error Formulation

Generic ingredients, limited data, and unpredictable outcomes.

  • Broad-spectrum, one-size-fits-all
  • Limited or absent clinical backing
  • No biological simulation
  • Slow iteration cycles

Enbiosis Approach

Digital Twin & AI-Driven Formulation

We simulate how the microbiome transforms ingredients into functional metabolites before a formulation ever reaches production.

  • Peer-reviewed scientific validation
  • AI-modelled ingredient-to-metabolite interactions
  • Optimised through large-scale digital twin simulations
  • Designed to target specific metabolic pathways

The Pipeline

How We Build Formulations

  1. Petri dish holding a turquoise bacterial colony grown in a spiral pattern

    Prediction

    1. Microbiome data
    2. Digital twin simulation
    3. Metabolic output prediction
  2. Small glass vials of turquoise liquid beside a dried root slice on marble

    Discovery

    1. Target metabolites
    2. Retrosynthesis modelling
    3. Precursor identification
  3. A capsule surrounded by grains, seeds and dried botanicals on a plain surface

    Design

    1. Food-grade substrates
    2. Minimal precursor sets
    3. Targeted formulation design
  4. Unbranded supplement sachets and amber bottles arranged on a white surface

    Validation

    1. Targeted formulation design
    2. Large-scale RCT validation
    3. Clinical evidence

Validation

Clinical Trials

Our platform is being validated through pilot and randomized clinical studies across multiple health areas, starting with ophthalmology and expanding into metabolic, gastrointestinal, and urology-focused indications.

  • Ophthalmology / Eye Health

    Dry Eye Disease (DED), Pilot study completed in DED

    RCT Ongoing

  • Metabolic

    Type 2 Diabetes Mellitus, Weight Management

    RCT Ongoing

  • Gastrointestinal

    Ulcerative Colitis

    RCT registered, starting

  • Dermatology

    Psoriasis

    RCT planned

  • Urology

    Hypogonadism

    RCT Ongoing

  • Neurological / Cognitive

    Alzheimer’s Disease, Parkinson’s Disease

    Planned

Publications

Peer-Reviewed Research

Our research is published in peer-reviewed journals across gastroenterology, microbiome science and machine learning.